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Postdoc at The Francis Crick Institute
London, United Kingdom
Job Descrption
Short summary
Dr Bishop is seeking a talented and motivated postdoc to study the function of the HIV Vpr protein during HIV infection.
The successful applicant will investigate how Vpr impacts the cell and how this promotes viral replication. The project will initially focus on Vpr-induced DNA damage and the effects on chromatin, but all aspects of Vpr biology may be investigated.
Postdoctoral Fellows are expected to lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and guide PhD students in their research. The ability to work in a team is essential.
Dr Bishop’s laboratory focuses on the early, post-entry replication of retroviruses including HIV and MLV. She is interested in understanding the molecular events that occur when a retrovirus infects its target cell in order to fully understand retroviral replication and provide potential ways in which to manipulate these processes for... the benfit of human health. Details of current research projects can be seen at: Her lab uses a wide range of research techniques including virological, biochemical and microscopy techniques and she collaborates closely with structural biologists.
The successful applicant will investigate the function and cellular targets of Vpr during HIV-1 replication, focusing initially on Vpr-induced DNA damage and how this promotes viral replication.
Key experience and competencies
Essential
• PhD in virology, cell biology or molecular biology
• Good knowledge and understanding of retrovirology
• Expertise in molecular biology and biochemical techniques
• Expertise in cell culture and transfection
• Pro-active in innovation and problem solving
• Experience of experimental design
• Track record of writing papers as evidenced by publications or submitted manuscripts in referred journals
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